This medication can be behavior-forming. If you think that the medication is not working in addition, tend not to use greater than your prescribed dose. Contact your medical professional for Directions.

Renal impairment: The kidney is the major route of elimination, so pharmacokinetics is altered in individuals with renal impairment. As a result, clinicians ought to prescribe codeine at a lessened dose or with longer dosing intervals.

Because of the dangers of dependancy, abuse, and misuse with opioids, even at proposed doses [see Warnings and Safety measures (5.1) ], reserve Promethazine with Codeine Oral Solution for use in adult clients for whom some great benefits of cough suppression are expected to outweigh the threats, As well as in whom an adequate evaluation of your etiology on the cough is created.

Urine drug screening, capsule counts, caregiver or loved one encounters, and prescription monitoring plan information is usually useful checking resources for people on steady doses and having a very low chance for adverse results; monitoring each and every three to six months could possibly be satisfactory. Weekly checking is an inexpensive method for individuals at substantial threat for abuse.[24]

Will not flush medicines down the bathroom or pour them into a drain Except instructed to take action. Correctly discard this product or service Promethazine codeine syrup when it is expired or now not wanted. Consult your pharmacist or community waste disposal organization.

If you're getting operation, such as dental surgery, explain to the health practitioner or dentist that you're having promethazine.

It is critical you comprehend the rules of the Opioid Analgesic REMS method to forestall habit, abuse, and misuse of codeine.

When you are having this medicine, it is especially critical that the healthcare Specialist know If you're using any on the medicines shown beneath. The following interactions are already picked on The idea in their likely significance and so are not automatically all-inclusive.

Using this medicine with any of the following medicines is not encouraged. Your medical doctor could come to a decision not to deal with you using this medication or transform a number of the other medicines you're taking.

Remedy of toxicity depends on both the signs and diploma of intoxication. Toxicity entails symptomatic cure (ie, enema for constipation) and definitive reversal While using the opioid antagonist naloxone for all times-threatening adverse effects like respiratory depression.

Acute or intense bronchial bronchial asthma in an unmonitored setting or in absence of resuscitative products. (4)

Stomach or bowel blockage (like paralytic ileus)—Shouldn't be used in individuals with these circumstances.

Other side effects not listed might also occur in a few sufferers. When you observe every other results, Test with the healthcare Specialist.

Most MAO inhibitors must also not be taken for 2 months in advance of cure with this particular medication. Inquire your medical professional when to begin or halt using this medication.